Journal of the American Academy of Dermatology
Volume 56, Issue 1 , Pages 27-30, January 2007

Gadolinium deposition in nephrogenic fibrosing dermopathy

  • Alan S. Boyd, MD

      Affiliations

    • From the Departments of Medicine (Dermatology)
    • Pathology, Vanderbilt University, Nashville
    • Corresponding Author InformationCorrespondence to: Alan S. Boyd, MD, 3900 The Vanderbilt Clinic, Nashville, TN 37232.
    • ,
  • John A. Zic, MD

      Affiliations

    • From the Departments of Medicine (Dermatology)
    • ,
  • Jerrold L. Abraham, MD

      Affiliations

    • Department of Pathology, SUNY Upstate Medical University, Syracuse

Accepted 27 October 2006. published online 17 November 2006.

Nashville, Tennessee, and Syracuse, New York

There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF). The pathogenesis of this entity remains unclear; however, our recent observations suggest a likely mechanism for the initial dermal manifestations of this gadolinium toxicity.

 

 Funding sources: None.Conflicts of interest: None identified.Reprints not available from the authors.

PII: S0190-9622(06)02878-7

doi:10.1016/j.jaad.2006.10.048

Journal of the American Academy of Dermatology
Volume 56, Issue 1 , Pages 27-30, January 2007