Journal of the American Academy of Dermatology
Volume 56, Issue 5 , Pages 781-785 , May 2007

Tea consumption and basal cell and squamous cell skin cancer: Results of a case-control study

  • Judy R. Rees, BM, BCh, PhD

      Affiliations

    • From the Departments of Community and Family Medicine (Section of Biostatistics and Epidemiology)
    • Dartmouth College Center for Environmental Health Sciences, Hanover
    • Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon
    • Corresponding Author InformationReprint requests: Judy R. Rees, BM, BCh, PhD, One Medical Center Dr, 7927 Rubin Bldg, Lebanon, NH 03756.
    • ,
  • Therese A. Stukel, PhD

      Affiliations

    • Institute for Clinical Evaluative Sciences, Toronto
    • ,
  • Ann E. Perry, MD

      Affiliations

    • Pathology
    • ,
  • Michael S. Zens, PhD

      Affiliations

    • From the Departments of Community and Family Medicine (Section of Biostatistics and Epidemiology)
    • ,
  • Steven K. Spencer, MD

      Affiliations

    • Medicine, Dartmouth Medical School, Lebanon
    • ,
  • Margaret R. Karagas, PhD

      Affiliations

    • From the Departments of Community and Family Medicine (Section of Biostatistics and Epidemiology)
    • Dartmouth College Center for Environmental Health Sciences, Hanover
    • Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon

,Accepted 26 November 2006.

References 

  1. Karagas MR, Greenberg ER, Spencer SK, Stukel TA, Mott LA. Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA. New Hampshire Skin Cancer Study Group. Int J Cancer. 1999;81:555–559
  2. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10–30Erratum in: CA Cancer J Clin 2005;55:259
  3. Higashi MK, Veenstra DL, Langley PC. Health economic evaluation of non-melanoma skin cancer and actinic keratosis. Pharmacoeconomics. 2004;22:83–94
  4. IARC monographs on the evaluation of carcinogenic risks to humans. Solar and ultraviolet radiation. IARC Monogr Eval Carcinog Risks Hum. 1992;55:1–316
  5. Einspahr JG, Stratton SP, Bowden GT, Alberts DS. Chemoprevention of human skin cancer. Crit Rev Oncol Hematol. 2002;41:269–285
  6. Kuroda Y, Hara Y. Antimutagenic and anticarcinogenic activity of tea polyphenols. Mutat Res. 1999;436:69–97
  7. Mukhtar H, Ahmad N. Mechanism of cancer chemopreventive activity of green tea. Proc Soc Exp Biol Med. 1999;436:234–238
  8. Yang CS, Chung JY, Yang G, Chhabra SK, Lee MJ. Tea and tea polyphenols in cancer prevention. J Nutr. 2000;130(2S Suppl):472S–478S
  9. Mukhtar H, Ahmad N. Green tea in chemoprevention of cancer. Toxicol Sci. 1999;52(2 Suppl):111–117
  10. Hakim IA, Harris RB, Weisgerber UM. Tea intake and squamous cell carcinoma of the skin: influence of type of tea beverages. Cancer Epidemiol Biomarkers Prev. 2000;9:727–731
  11. Milan T, Verkasalo PK, Kaprio J, Koskenvuo M. Lifestyle differences in twin pairs discordant for basal cell carcinoma of the skin. Br J Dermatol. 2003;149:115–123
  12. Corona R, Dogliotti E, D'Errico M. Risk factors for BCC in a Mediterranean population. Arch Dermatol. 2001;137:1162–1168
  13. Karagas MR, Tosteson TD, Blum J, Morris JS, Baron JA, Klaue B. Design of an epidemiologic study of drinking water arsenic exposure and skin and bladder cancer risk in a U.S. population. Environ Health Perspect. 1998;106(Suppl 4):1047–1050
  14. Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr. 2000;71(6 Suppl):1698S–1702Sdiscussion 1703S-4S
  15. Gupta S, Mukhtar H. Chemoprevention of skin cancer: current status and future prospects. Cancer Metastasis Rev. 2002;21:363–380
  16. Katiyar SK, Matsui MS, Elmets CA, Mukhtar H. Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem Photobiol. 1999;69:148–153
  17. Katiyar SK, Perez A, Mukhtar H. Green tea polyphenol treatment to human skin prevents formation of ultraviolet light B-induced pyrimidine dimers in DNA. Clin Cancer Res. 2000;6:3864–3869

 Supported by grant CA57494 from the National Institute of Health, National Cancer Institute.Conflicts of interest: None declared.

PII: S0190-9622(06)04103-X

doi: 10.1016/j.jaad.2006.11.038

Journal of the American Academy of Dermatology
Volume 56, Issue 5 , Pages 781-785 , May 2007

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