Journal of the American Academy of Dermatology
Volume 58, Issue 6 , Pages 1000-1005, June 2008

Nickel release from earrings purchased in the United States: The San Francisco earring study

  • Jacob Pontoppidan Thyssen, MD

      Affiliations

    • National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, Gentofte, Denmark
    • Department of Dermatology, School of Medicine, University of California, San Francisco, California
    • Corresponding Author InformationReprint requests: Jacob Pontoppidan Thyssen, MD, National Allergy Research Centre, Department of Dermatology, Gentofte University Hospital, Ledreborg Allé 40, 1. 2820 Gentofte, Denmark.
  • ,
  • Howard Ira Maibach, MD

      Affiliations

    • Department of Dermatology, School of Medicine, University of California, San Francisco, California

Accepted 4 March 2008. published online 14 April 2008.

Background

Nickel sensitization is frequent among US patients with dermatitis and in the general population. In Europe, decreasing prevalences of nickel sensitization are observed as a result of the European Union Nickel Directive. However, no directive exists in the United States.

Objectives

We sought to examine nickel release from inexpensive earrings and discuss possible methods of reducing nickel exposure among consumers.

Methods

A total of 34 different stores and artists were visited. A total of 277 earrings were purchased and examined with the dimethylglyoxime (DMG) test.

Results

DMG-positive earrings were identified from local artists (69%) and tourist stores (42.9%) but also chain stores targeting young (24.1%) and mature (1.7%) women. No correlation between price and outcome of DMG testing was identified.

Limitations

Our study does not reflect buying trends in the United States. Pretreatment of earrings with artificial sweat was not performed and the DMG may lead to both false-positive and false–negative results.

Conclusions

Nickel exposure from inexpensive earrings is frequent in the United States. A regulatory governmental intervention may be warranted.

Abbreviations used: DMG, dimethylglyoxime, EU, European Union, NACDG, North American Contact Dermatitis Group

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 Supported by the Copenhagen County Research Foundation and the Foundation of Danish Physicians under CODAN/SEB.

 Conflicts of interest: None declared.

PII: S0190-9622(08)00359-9

doi:10.1016/j.jaad.2008.03.017

Journal of the American Academy of Dermatology
Volume 58, Issue 6 , Pages 1000-1005, June 2008