Journal of the American Academy of Dermatology
Volume 59, Issue 4 , Pages 577-581 , October 2008

Adherence to acitretin and home narrowband ultraviolet B phototherapy in patients with psoriasis

  • Brad A. Yentzer, MD

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Christopher B. Yelverton, MD, MBA

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Daniel J. Pearce, MD

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Fabian T. Camacho, MS

      Affiliations

    • Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Zaineb Makhzoumi, BS

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Adele Clark, PA-C

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Ann Boles, RN, CCRC

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Alan B. Fleischer Jr., MD

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • ,
  • Rajesh Balkrishnan, PhD

      Affiliations

    • Ohio State University College of Pharmacy and School of Public Health, Columbus, Ohio
    • ,
  • Steven R. Feldman, MD, PhD

      Affiliations

    • Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina
    • Corresponding Author InformationCorrespondence to: Steven R. Feldman, MD, PhD, Department of Dermatology, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157-1071.

,Accepted 3 June 2008.

References 

  1. Kampitak T, Asawanonda P. The efficacy of combination treatment with narrowband UVB (TL-01) and acitretin vs narrowband UVB alone in plaque-type psoriasis: a retrospective study. J Med Assoc Thai. 2006;89(Suppl):S20–S24
  2. Spuls PI, Rozenblit M, Lebwohl M. Retrospective study of the efficacy of narrowband UVB and acitretin. J Dermatolog Treat. 2003;14(Suppl):17–20
  3. Feldman SR, Koo JY, Lebwohl MG, Menter A, Van Voorhees A. The psoriasis and psoriatic arthritis pocket guide: treatment algorithms and management options. Portland, OR: National Psoriasis Foundation. Pamphlet; 2005;
  4. Feldman SR, Garton R, Averett W, Balkrishnan R, Vallee J. Strategy to manage the treatment of severe psoriasis: considerations of efficacy, safety and cost. Expert Opin Pharmacother. 2003;4:1525–1533
  5. Yelverton CB, Kulkarni AS, Balkrishnan R, Feldman SR. Home ultraviolet B phototherapy: a cost-effective option for severe psoriasis. Manag Care Interface. 2006;19:33–3639
  6. Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Investig Dermatol Symp Proc. 2004;9:136–139
  7. Stone AA, Shiffman S, Schwartz JE, Broderick JE, Hufford MR. Patient compliance with paper and electronic diaries. Control Clin Trials. 2003;24:182–199
  8. Carroll CL, Feldman SR, Camacho FT, Manuel JC, Balkrishnan R. Adherence to topical therapy decreases during the course of an 8-week psoriasis clinical trial: commonly used methods of measuring adherence to topical therapy overestimate actual use. J Am Acad Dermatol. 2004;51:212–216
  9. Cramer JA, Mattson RH, Prevey ML, Scheyer RD, Ouellette VL. How often is medication taken as prescribed? A novel assessment technique. JAMA. 1989;261:3273–3277
  10. Yelverton CB, Balkrishnan R, Feldman SR. The utility of a data-logging device for measuring adherence to home phototherapy. Photodermatol Photoimmunol Photomed. 2006;22:270–272
  11. Griffith S. A review of the factors associated with patient compliance and the taking of prescribed medicines. Br J Gen Pract. 1990;40:114–116
  12. Young SD, Oppenheimer DM. Different methods of presenting risk information and their influence on medication compliance intentions: results of three studies. Clin Ther. 2006;28:129–139
  13. Carr AJ, Thompson PW, Cooper C. Factors associated with adherence and persistence to bisphosphonate therapy in osteoporosis: a cross-sectional survey. Osteoporos Int. 2006;17:1638–1644
  14. Feldman SR, Camacho FT, Krejci-Manwaring J, Carroll CL, Balkrishnan R. Adherence to topical therapy increases around the time of office visits. J Am Acad Dermatol. 2007;57:81–83

 Supported by National Biologic Corporation and Connetics.

 Disclosure: Dr Feldman has received research, speaking, and/or consulting support from Connetics, Roche, Amgen, Biogen, and Genentech. Drs Yentzer, Yelverton, Pearce, Fleischer, and Balkrishnan; Mr Camacho; Ms Makhzoumi; Ms Clark; and Ms Boles have no conflicts of interest to declare.

 Reprints not available from the authors.

PII: S0190-9622(08)00660-9

doi: 10.1016/j.jaad.2008.06.007

Journal of the American Academy of Dermatology
Volume 59, Issue 4 , Pages 577-581 , October 2008

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