Journal of the American Academy of Dermatology
Volume 62, Issue 2 , Pages 324-329 , February 2010

Congenital pigment synthesizing melanoma of the scalp

  • Sook Jung Yun, MD, PhD

      Affiliations

    • Department of Dermatology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Dong Kyun Han, MD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Min-Cheol Lee, MD, PhD

      Affiliations

    • Department of Pathology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Jee-Bum Lee, MD, PhD

      Affiliations

    • Department of Dermatology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Hee Jo Baek, MD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Si Young Bae, MD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Tai Ju Hwang, MD, PhD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Sam Yong Lee, MD, PhD

      Affiliations

    • Department of Plastic Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Joon Kyoo Lee, MD, PhD

      Affiliations

    • Department of Otolaryngology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • ,
  • Hoon Kook, MD, PhD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School and Center for Biomedical Human Resources, Gwangju, Korea
    • Corresponding Author InformationReprint requests: Hoon Kook, MD, PhD, Department of Pediatrics, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, 160 Ilsim-Ri, Hwasun, Chollanamdo, 519-809, Korea (South).

References 

  1. Asai J, Takenaka H, Ikada S, Soga F, Kishimoto S. Congenital malignant melanoma: a case report. Br J Dermatol. 2004;151:693–697
  2. Richardson SK, Tannous ZS, Mihm MC. Congenital and infantile melanoma: review of the literature and report of an uncommon variant, pigment-synthesizing melanoma. J Am Acad Dermatol. 2002;47:77–90
  3. Eton O, Legha SS, Bedikian AY, Lee JJ, Buzaid AC, Hodges C, et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial. J Clin Oncol. 2002;20:2045–2052
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  6. Herron MD, Vanderhooft SL, Smock K, Zhou H, Leachman SA, Coffin C. Proliferative nodules in congenital melanocytic nevi: a clinicopathologic and immunohistochemical analysis. Am J Surg Pathol. 2004;28:1017–1025
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  8. Dick W. Melanosis in men and horses (letter). Lancet. 1832;192
  9. Crowson AN, Magro CM, Mihm MC. Malignant melanoma with prominent pigment synthesis. ‘Animal type’ melanoma-a clinical and histologic study of 6 cases with a consideration of other melanocytic neoplasms with prominent pigment synthesis. Hum Pathol. 1999;30:341–346
  10. Zembowicz A, Carney JA, Mihm MC. Pigmented epithelioid melanocytoma. Am J Surg Pathol. 2004;28:31–40
  11. Zembowicz A, Mihm MC. Dermal dendritic melanocytic proliferations: an update. Histopathology. 2004;45:433–451
  12. Leech SN, Bell H, Leonard N, Jones SL, Geurin D, Mckee PH, et al. Neonatal giant congenital nevi with proliferative nodules. A clinicopathologic study and literature review of neonatal melanoma. Arch Dermatol. 2004;140:83–88
  13. Palazzi MA, Ober MD, Abreu HFH, Cardinalli IA, Isaac CR, Odashiro AN, et al. Congenital uveal malignant melanoma: a case report. Can J Ophthalmol. 2005;40:611–615
  14. Kazakov DV, Rutten A, Kempf W, Michal M. Melanoma with prominent pigment synthesis (Animal-type melanoma), a case report and ultrastructural studies. Am J Dermatopathol. 2004;26:290–297
  15. Ferrara G, Soyer HP, Malvehy J, Piccolo D, Puig S, Sopena J, et al. The many faces of blue nevus: a clinicopathologic study. J Cutan Pathol. 2007;34:543–551
  16. Pearson JP, Weiss SW, Headington JT. Cutaneous malignant melanotic neurocristic tumors arising in neurocristic hamartomas: a melanocytic tumor morphologically and biologically distinct from common melanoma. Am J Surg Pathol. 2006;20:665–677
  17. Rongioletti F, Smoller BR. Unusual histological variants of cutaneous malignant melanoma with some clinical and possible prognostic correlations. J Cutan Pathol. 2005;32:589–603

 Drs Yun and Han contributed equally to all aspects of this manuscript.

 Funding sources: None.

 Conflicts of interest: None declared.

PII: S0190-9622(08)00916-X

doi: 10.1016/j.jaad.2008.07.025

Journal of the American Academy of Dermatology
Volume 62, Issue 2 , Pages 324-329 , February 2010

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