Journal of the American Academy of Dermatology
Volume 59, Issue 5 , Pages 772-780, November 2008

The impact of psoriasis on health care costs and patient work loss

  • Joseph F. Fowler, MD

      Affiliations

    • University of Louisville, Louisville, Kentucky
  • ,
  • Mei Sheng Duh, MPH, ScD

      Affiliations

    • Analysis Group, Inc, Boston, Massachusetts
  • ,
  • Ludmila Rovba, PhD

      Affiliations

    • Analysis Group, Inc, Boston, Massachusetts
  • ,
  • Sharon Buteau, MA

      Affiliations

    • Analysis Group, Inc, Boston, Massachusetts
  • ,
  • Lisa Pinheiro, MS

      Affiliations

    • Analysis Group, Inc, Boston, Massachusetts
  • ,
  • Francis Lobo, PhD

      Affiliations

    • Novartis Pharmaceuticals Corp, East Hanover, New Jersey
  • ,
  • Jennifer Sung, MS, PharmD

      Affiliations

    • Novartis Pharmaceuticals Corp, East Hanover, New Jersey
  • ,
  • Joseph J. Doyle, RPh, MBA

      Affiliations

    • Novartis Pharmaceuticals Corp, East Hanover, New Jersey
  • ,
  • Andrine Swensen, MS, PhD

      Affiliations

    • Novartis Pharmaceuticals Corp, East Hanover, New Jersey
  • ,
  • David A. Mallett, MBA, MHA

      Affiliations

    • Ingenix, Inc, New Haven, Connecticut
  • ,
  • George Kosicki, PhD

      Affiliations

    • Analysis Group, Inc, Boston, Massachusetts
    • Corresponding Author InformationReprint requests: George Kosicki, PhD, Analysis Group, Inc, 111 Huntington Ave, 10th Floor, Boston, MA 02199.

Accepted 24 June 2008.

Background

There are few comprehensive estimates of the cost of psoriasis in the United States.

Objective

We sought to quantify the incremental direct medical and indirect work loss costs associated with psoriasis.

Methods

A de-identified claims database from 31 self-insured employers during the period 1998 to 2005 was used. Patients with at least two psoriasis diagnosis claims (N = 12,280) were compared with 3 control subjects (matched on year of birth and sex) without psoriasis. Multivariate two-part regression analysis was used to isolate the incremental cost of psoriasis by controlling for comorbidities and other confounding factors.

Results

After multivariate adjustment, the incremental direct and indirect costs of psoriasis were approximately $900 and $600 (P < .001) per patient per year, respectively.

Limitations

The database used in this study does not contain information on patient out-of-pocket costs or loss of productivity costs at work.

Conclusion

The incremental cost of psoriasis is approximately $1500 per patient per year, with work loss costs accounting for 40% of the cost burden.

Abbreviations used: HMO, health maintenance organization, OTC, over the counter, PPPM, per patient per month

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 Supported by Novartis Pharmaceuticals Corp.

 Disclosure: Dr Swensen, Dr Sung, Mr Doyle, and Dr Lobo are employees of and Dr Fowler, Dr Duh, Dr Rovba, Ms Buteau, Ms Pinheiro, Mr Mallett, and Dr Kosicki are consultants to Novartis Pharmaceuticals Corp.

 Presented in part at the following poster sessions: 65th Annual Meeting of the American Academy of Dermatology, Washington, DC, February 2-6, 2007, and 12th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research, Arlington, VA, May 19-23, 2007.

PII: S0190-9622(08)01014-1

doi:10.1016/j.jaad.2008.06.043

Journal of the American Academy of Dermatology
Volume 59, Issue 5 , Pages 772-780, November 2008