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Journal of the American Academy of Dermatology
Volume 61, Issue 5
, Pages 819-828
, November 2009
Lymphatic invasion detected by D2-40/S-100 dual immunohistochemistry does not predict sentinel lymph node status in melanoma
References
- Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol. 2001;19:3635–3648
- Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol. 2001;19:3622–3634
- The sentinel lymph node status is an important factor for predicting clinical outcome in patients with stage I or II cutaneous melanoma. Cancer. 2001;91:2401–2408
- Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients. J Clin Oncol. 1999;17:976–983
- Outcome in 846 cutaneous melanoma patients from a single center after a negative sentinel node biopsy. Ann Surg Oncol. 2005;12:429–439
- . Reliability of sentinel lymph node biopsy for staging melanoma. Br J Surg. 2000;87:484–489
- Clinical significance of occult metastatic melanoma in sentinel lymph nodes and other high-risk factors based on long-term follow-up. World J Surg. 2005;29:683–691
- . Sentinel lymph node biopsy in cutaneous melanoma: a case-control study. Ann Surg Oncol. 2007;14:3566–3574
- . Sentinel lymph node biopsy in patients with primary cutaneous melanoma: study of 455 cases. J Eur Acad Dermatol Venereol. 2000;14:35–45
- Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med. 2006;355:1307–1317
- . Sentinel-node biopsy in melanoma. N Engl J Med. 2006;355:1370–1371
- Patients with lymphatic metastasis of cutaneous malignant melanoma benefit from sentinel lymphadenectomy and early excision of their nodal disease. Eur J Cancer. 2004;40:212–218
- . Lymph node status and survival in cutaneous malignant melanoma-sentinel lymph node biopsy impact. Eur J Surg Oncol. 2003;29:611–618
- . The survival benefit to patients with positive sentinel node melanoma after completion lymph node dissection may be limited to the subgroup with a primary lesion Breslow thickness greater than 1.0 and less than or equal to 4 mm (pT2-pT3). Ann Surg Oncol. 2008;15:2223–2234
- Importance of sentinel lymph node biopsy in patients with thin melanoma. Arch Surg. 2008;143:892–899
- Regional nodal metastatic disease is the strongest predictor of survival in patients with thin vertical growth phase melanomas: a case for SLN staging biopsy in these patients. Ann Surg Oncol. 2007;14:1596–1603
- Improved staging of node-negative patients with intermediate to thick melanomas (>1 mm) with the use of lymphatic mapping and sentinel lymph node biopsy. Ann Surg Oncol. 2001;8:766–770
- . The risk of regional lymph node metastases in patients with melanomas less than 1.0 mm thick: recommendations for sentinel lymph node biopsy. J Am Coll Surg. 2003;197:403–407
- Indications for lymphatic mapping and sentinel lymphadenectomy in patients with thin melanoma (Breslow thickness < or =1.0 mm). Ann Surg Oncol. 2004;11:900–906
- . Sentinel lymph node mapping for thick (>or=4-mm) melanoma: should we be doing it?. Ann Surg Oncol. 2003;10:408–415
- Mitotic rate as a predictor of sentinel lymph node positivity in patients with thin melanomas. Ann Surg Oncol. 2005;12:449–458
- . Tumor thickness as a predictor of occult lymph node metastases in patients with stage I and II melanoma undergoing sentinel lymph node biopsy. Br J Surg. 2002;89:1223–1227
- Revised American Joint Committee on Cancer staging criteria accurately predict sentinel lymph node positivity in clinically node-negative melanoma patients. Ann Surg Oncol. 2003;10:569–574
- Melanoma thickness and histology predict sentinel lymph node status. Am J Surg. 2001;181:8–11
- . Prediction of sentinel lymph node micrometastasis by histologic features in primary cutaneous malignant melanoma. Arch Dermatol. 1998;134:983–987
- Clinical and dermoscopic criteria related to melanoma sentinel lymph node positivity. Anticancer Res. 2007;27:2939–2944
- The correlation of regression in primary melanoma with sentinel lymph node status. J Clin Pathol. 2008;61:297–300
- Predictors of regional nodal disease in patients with thin melanomas. Ann Surg Oncol. 2006;13:533–541
- Relationship between sentinel lymph node status and regression in primary malignant melanoma. Melanoma Res. 2005;15:509–513
- Predicting sentinel and residual lymph node basin disease after sentinel lymph node biopsy for melanoma. Cancer. 2000;89:453–462
- Small cell melanoma and ulceration as predictors of positive sentinel lymph node in malignant melanoma patients. Melanoma Res. 2004;14:277–282
- . A nomogram that predicts the presence of sentinel node metastasis in melanoma with better discrimination than the American Joint Committee on Cancer staging system. Ann Surg Oncol. 2005;12:282–288
- The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma. Cancer. 2007;109:100–108
- Mitotic rate and younger age are predictors of sentinel lymph node positivity: lessons learned from the generation of a probabilistic model. Ann Surg Oncol. 2004;11:247–258
- . Targeting lymphatic metastasis. Science. 2002;296:1811–1812
- . Tumor lymphangiogenesis and melanoma metastasis. J Cell Physiol. 2008;216:346–354
- . New insights into the biology and pathology of the cutaneous lymphatic system. J Dermatol Sci. 2004;35:1–8
- Lymphatic density and metastatic spread in human malignant melanoma. Br J Cancer. 2004;90:693–700
- Tumour lymphangiogenesis is a possible predictor of sentinel lymph node status in cutaneous melanoma: a case-control study. J Clin Pathol. 2006;59:166–173
- Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival. Am J Pathol. 2003;162:1951–1960
- Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes. Mod Pathol. 2005;18:1232–1242
- . The use of LYVE-1 antibody for detecting lymphatic involvement in patients with malignant melanoma of known sentinel node status. J Clin Pathol. 2005;58:715–721
- . Expression pattern of the lymphatic and vascular markers VEGFR-3 and CD31 does not predict regional lymph node metastasis in cutaneous melanoma. Arch Dermatol Res. 2006;297:352–357
- . Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma. Clin Cancer Res. 2003;9:250–256
- . Lymphatic vessel density and prognosis in cutaneous melanoma. Br J Cancer. 2004;91:1224–1225
- . Comparison of the diagnostic accuracy of lymphatic endothelium markers: Bayesian approach. Mod Pathol. 2005;18:1490–1497
- . Upregulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005;66:913–921
- . A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest. 2002;82:1255–1257
- . Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol. 2002;15:434–440
- . Detection of lymphatic invasion in primary melanoma with monoclonal antibody D2-40: a new selective immunohistochemical marker of lymphatic endothelium. Arch Dermatol. 2005;141:440–444
- . Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer. Mod Pathol. 2007;20:183–191
- . Detection of lymphatic invasion in early stage primary colorectal cancer with the monoclonal antibody D2-40. Eur Surg Res. 2006;38:438–444
- . Lymphatic invasion according to D2-40 immunostaining is a predictor of nodal metastasis in endometrioid adenocarcinoma of the uterine corpus. Pathol Int. 2008;58:471–476
- Lymphatic invasion according to D2-40 immunostaining is a strong predictor of nodal metastasis in superficial squamous cell carcinoma of the esophagus: algorithm for risk of nodal metastasis based on lymphatic invasion. Pathol Int. 2008;58:282–287
- . SAS/STAT® 9.1 User's Guide. Cary (NC): SAS Institute Inc; 2004;
- Lymphatic invasion identified by monoclonal antibody D2-40, younger age, and ulceration: predictors of sentinel lymph node involvement in primary cutaneous melanoma. Arch Dermatol. 2008;144:462–467
- . Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasis. J Cutan Pathol. 2008 Nov 5;[Epub ahead of print]
- Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis. Hum Pathol. 2008;39:901–909
Supported by a grant from the Stephen Short Memorial Fund from the Department of Dermatology, University of Texas Medical Branch.
Conflicts of interest: None declared.
Presented as a poster at the 45th Annual Meeting of the American Society of Dermatopathology, San Francisco, CA, October 16-19, 2008.
PII: S0190-9622(09)00504-0
doi: 10.1016/j.jaad.2009.04.026
© 2009 American Academy of Dermatology, Inc. Published by Elsevier Inc All rights reserved.
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Journal of the American Academy of Dermatology
Volume 61, Issue 5
, Pages 819-828
, November 2009
