Journal of the American Academy of Dermatology
Volume 61, Issue 4 , Pages e15-e21 , October 2009

Cutaneous leishmaniasis in North-Western Yemen: A clinicoepidemiologic study and Leishmania species identification by polymerase chain reaction–restriction fragment length polymorphism analysis

  • Mishri Lal Khatri, MD

      Affiliations

    • Department of Dermatology, Saudi Hospital at Hajjah, Sana'a, Yemen Republic
    • Corresponding Author InformationReprint requests: Mishri Lal Khatri, MD, Saudi Hospital at Hajjah, PO Box: 2757, Sana'a, Yemen Republic.
    • ,
  • Trentina Di Muccio, MD

      Affiliations

    • Vector-borne Diseases and International Health, Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy
    • ,
  • Marina Gramiccia, MD

      Affiliations

    • Vector-borne Diseases and International Health, Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

,Accepted 20 April 2009.

References 

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  2. Rioux JA, Daoud W, Pratlong F, El Kûbati Y, Moreno G, Rageh HA, et al. Les complexes Leishmania donovani s.st. In:  Rioux JA editors. Leishmania tropica et Leishmania major en République Arabe du Yémen. In: Rious JA, ed. Leishmania: Taxonomie-Phylogenèse. Applications éco-épidemiologiques. Montpellier: Institut Méditerranéen d'Etudes Epidemiologiques et Ecologiques; 1986;p. 357–363
  3. Rioux JA, Dereure J, Daoud W, El Kubati Y, Rageh HA, Moreno G, et al. Eco-epidemiology of visceral and cutaneous leishmaniasis in the Yemen Arab Republic. I. Presence, in sympatric condition, of Leishmania infantum and Leishmania donovani complexes. Bull Soc Pathol Exot Filiales. 1989;82:658–664
  4. Pratlong F, Bastien P, Perello R, Lami P, Dedet JP. Human cutaneous leishmaniasis caused by Leishmania donovani sensu stricto in Yemen. Trans R Soc Trop Med Hyg. 1995;89:398–399
  5. Khatri ML, Haider N, Di Muccio T, Gramiccia M. Cutaneous leishmaniasis in Yemen: Clinicoepidemiologic features and a preliminary report on species identification. Int J Dermatol. 2006;46:40–45
  6. Minodier P, Piaroux R, Gambarelli F, Joblet C, Dumon H. Rapid Identification of Causative Species in Patients with Old World Leishmaniasis. J Clin Microbiol. 1997;35:2551–2555
  7. Gramiccia M, Di Muccio T, Marinucci M. Parasite identification in the surveillance of imported leishmaniasis cases in Italy. Parasitologia. 2004;46:207–210
  8. Mathis A, Deplazes P. PCR and in vitro cultivation for detection of Leishmania spp. in diagnostic samples from humans and dogs. J Clin Microbiol. 1995;3:1145–1149
  9. Malik GM, Ahmed SM. Cutaneous leishmaniasis in Asir region, southern Saudi Arabia. Ann Saudi Med. 1991;11:591
  10. Al-Zahrani MA, Peters W, Evans DA, Smith V, Ching Chin I. Leishmaniasis infecting man and wild animals in Saudi Arabia. 6. Cutaneous leishmaniasis of man in southwest. Trans R Soc Trop Med Hyg. 1989;83:621–628
  11. Hossain A, Bolbol AS, Bakir TMF, Siddiqui MA, Raj MR, Kumarsinghe G. Cutaneous leishmaniasis in Saudi Arabia. J R Soc Health. 1988;108:60–61
  12. Morsy TA, Khalil NM, Salama MM, Hamdi KN, Al-Shamrany YA, Abdulla KF. Mucosal leishmaniasis caused by Leishmania tropica in Saudi Arabia. J Egypt Soc Parasitol. 1995;25:73–79
  13. Sitheesque MA, Quazzi AA, Ahmed GA. A study of cutaneous leishmaniasis involvement of the lip and perioral tissue. Br J Oral Maxillo-Fac Surg. 1990;28:43–46
  14. Kubba R, El-Hassan AM, Al-Gindan Y, Omer AH, Kutty MK, Saeed MB. Dissemination in cutaneous leishmaniasis. I. Subcutaneous nodules. Int J Dermatol. 1987;26:300–304
  15. Al-Qurashi AR, Ghandour AM, Osman M, Al-Juma M. Dissemination in cutaneous leishmaniasis due to Leishmania major in different ethnic groups in Saudi Arabia. Int J Dermatol. 2000;39:832–836
  16. Khatri ML, Shafi M, Benghazil M. Cutaneous leishmaniasis with unusual presentation. Ind J Dermatol Venereol Leprol. 1999;65:140–142
  17. Meziou TJ, Chaabene H, Masmoudi A, Boudaya S, Cheikhrouhou H, Bouassida SH, et al. Disseminated cutaneous leishmaniasis secondary to lymphoedema: two cases. Ann Dermatol Venereol. 2008;21:106–107
  18. Gebre-Michael T, Balkew M, Ali A, Ludovici A, Gramiccia M. The isolation of Leishmania tropica and L. aethiopica from Phlebotomus (Paraphlebotomus) species (Diptera: Psychodidae) in the Awash Valley, northeastern Ethiopia. Trans R Soc Trop Med Hyg. 2004;98:64–70
  19. Kubba R, Al-Gindan Y, El-Hassan AM, Omar AHS. Clinical diagnosis of cutaneous leishmaniasis (oriental sore). J Am Acad Dermatol. 1987;16:1183–1189

 Funding sources: None.

 Conflicts of interest: None declared.

 Proceedings of the study were presented, in part, at the 21st World Congress of Dermatology, Buenos Aires, Argentina, Oct 1-5, 2007.

PII: S0190-9622(09)00543-X

doi: 10.1016/j.jaad.2009.04.047

Journal of the American Academy of Dermatology
Volume 61, Issue 4 , Pages e15-e21 , October 2009

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