Journal of the American Academy of Dermatology
Volume 62, Issue 1 , Pages 67-75 , January 2010

Dermatoscopy of basal cell carcinoma: Morphologic variability of global and local features and accuracy of diagnosis

  • Davide Altamura, MD

      Affiliations

    • Department of Dermatology, University of L'Aquila, Italy
    • ,
  • Scott W. Menzies, MBBS, PhD

      Affiliations

    • Sydney Melanoma Diagnostic Center, Sydney Cancer Center, Royal Prince Alfred Hospital, Camperdown, and Discipline of Dermatology, University of Sydney, Sydney, Australia
    • ,
  • Giuseppe Argenziano, MD

      Affiliations

    • Department of Dermatology, Second University of Naples, Naples, Italy
    • ,
  • Iris Zalaudek, MD

      Affiliations

    • Department of Dermatology, Medical University of Graz, Graz, Austria
    • ,
  • H. Peter Soyer, MD, FACD

      Affiliations

    • Dermatology Research Center, The University of Queensland, School of Medicine, Princess Alexandra Hospital, Brisbane, Australia
    • ,
  • Francesco Sera, DStat

      Affiliations

    • Molecular and Nutritional Epidemiology Unit, Cancer Prevention and Research Institute, Florence, Italy
    • ,
  • Michelle Avramidis, BSc

      Affiliations

    • Sydney Melanoma Diagnostic Center, Sydney Cancer Center, Royal Prince Alfred Hospital, Camperdown, and Discipline of Dermatology, University of Sydney, Sydney, Australia
    • ,
  • Kathryn DeAmbrosis, MBBS

      Affiliations

    • Dermatology Research Center, The University of Queensland, School of Medicine, Princess Alexandra Hospital, Brisbane, Australia
    • ,
  • Maria Concetta Fargnoli, MD

      Affiliations

    • Department of Dermatology, University of L'Aquila, Italy
    • ,
  • Ketty Peris, MD

      Affiliations

    • Department of Dermatology, University of L'Aquila, Italy
    • Corresponding Author InformationReprint requests: Ketty Peris, MD, Department of Dermatology, University of L'Aquila, Via Vetoio - Coppito 2, 67100 L'Aquila, Italy.

,Accepted 17 May 2009.

References 

  1. Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, Kerl H. Epidemiology and etiology of basal cell carcinoma. Br J Dermatol. 2007;157(Suppl):47–51
  2. Leiter U, Garbe C. Epidemiology of melanoma and non-melanoma skin cancer–the role of sunlight. Adv Exp Med Biol. 2008;624:89–103
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  4. Kittler H, Pehamberger H, Wolff K, Binder M. Diagnostic accuracy of dermoscopy. Lancet Oncol. 2002;3:159–165
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  8. Menzies SW, Ingvar C, Crotty KA, McCarthy WH. Surface microscopy of pigmented basal cell carcinoma. Arch Dermatol. 2000;136:1012–1016
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  10. Felder S, Rabinovitz H, Oliviero M, Kopf A. Dermoscopic differentiation of a superficial basal cell carcinoma and squamous cell carcinoma in situ. Dermatol Surg. 2006;32:423–425
  11. Felder S, Rabinovitz H, Oliviero M, Kopf A. Dermoscopic pattern of pigmented basal cell carcinoma, blue-white variant. Dermatol Surg. 2006;32:569–570
  12. Rossiello L, Zalaudek I, Cabo H, Ferrara G, Gabriel C, Argenziano G. Dermoscopic-pathologic correlation in an unusual case of pigmented basal cell carcinoma. Dermatol Surg. 2006;32:1509–1512
  13. Zalaudek I, Ferrara G, Broganelli P, Moscarella E, Mordente I, Giacomel J, et al. Dermoscopy patterns of fibroepithelioma of pinkus. Arch Dermatol. 2006;142:1318–1321
  14. Giacomel J, Zalaudek I. Dermoscopy of superficial basal cell carcinoma. Dermatol Surg. 2005;31:1710–1713
  15. Scalvenzi M, Lembo S, Francia MG, Balato A. Dermoscopic patterns of superficial basal cell carcinoma. Int J Dermatol. 2008;47:1015–1018
  16. Menzies SW, Ingvar C, Crotty K, McCarthy W. Frequency and morphologic characteristics of invasive melanomas lacking specific surface microscopic features. Arch Dermatol. 1996;132:1178–1182
  17. Fleiss JL. Statistical methods for rates and proportions. 2nd ed.. New York: John Wiley and Sons; 1981;p. 212-36
  18. Sim J, Wright CC. The Kappa statistic in reliability studies: use, interpretation and sample size requirements. Phys Ther. 2005;85:257–268
  19. Peris K, Altobelli E, Ferrari A, Fargnoli MC, Piccolo D, Esposito M, et al. Interobserver agreement on dermoscopic features of pigmented basal cell carcinoma. Dermatol Surg. 2002;28:643–645
  20. Hoehler FK. Bias and prevalence effects on kappa viewed in terms of sensitivity and specificity. J Clin Epidemiol. 2000;53:499–503

 Funding sources: None.

 Conflicts of interest: None declared.

PII: S0190-9622(09)00664-1

doi: 10.1016/j.jaad.2009.05.035

Journal of the American Academy of Dermatology
Volume 62, Issue 1 , Pages 67-75 , January 2010

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