Journal of the American Academy of Dermatology
Volume 62, Issue 3 , Pages 463-468 , March 2010

Epidermotropic Merkel cell carcinoma: A case series with histopathologic examination

  • Mark D'Agostino, MD, MS, MSc

      Affiliations

    • Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • ,
  • Christina Cinelli, MD

      Affiliations

    • Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • ,
  • Robert Willard, MD

      Affiliations

    • Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • ,
  • Jeffrey Hofmann, MD

      Affiliations

    • Department of Surgery (Ophthalmology), Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • ,
  • Nathaniel Jellinek, MD

      Affiliations

    • Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • ,
  • Leslie Robinson-Bostom, MD

      Affiliations

    • Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island
    • Corresponding Author InformationCorrespondence to: Leslie Robinson-Bostom, MD, Department of Dermatology, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy St, APC-10, Providence, RI 02903.

References 

  1. Agelli M, Clegg LX. Epidemiology of primary Merkel cell carcinoma in the United States. J Am Acad Dermatol. 2003;49:832–841
  2. Skelton HG, Smith KJ, Hitchcock CL, Lupton GP, Graham JH. Merkel cell carcinoma: analysis of clinical, histologic, and immunologic features of 132 cases with relation to survival. J Am Acad Dermatol. 1997;37:734–739
  3. Feng H, Masahiro S, Chang Y, Moore P. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008;319:1096–1100
  4. Foulongne V, Kluger N, Dereure O, Brieu N, Guillot B, Segondy M. Merkel cell polyomavirus and Merkel cell carcinoma. Emerg Infect Dis. 2008;14:1491–1493
  5. Hashimoto K, Lee MW, D'Annunzio DR, Balle MR, Narisawa Y. Pagetoid Merkel cell carcinoma: epidermal origin of the tumor. J Cutan Pathol. 1998;25:572–579
  6. Traest K, De Vos R, van den Oord JJ. Pagetoid Merkel cell carcinomas: speculation on the origin and the mechanism of epidermal spread. J Cutan Pathol. 1999;26:362–365

 Funding sources: None.

 Conflicts of interest: None declared.

 Reprints not available from the authors.

PII: S0190-9622(09)00696-3

doi: 10.1016/j.jaad.2009.06.023

Journal of the American Academy of Dermatology
Volume 62, Issue 3 , Pages 463-468 , March 2010

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