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Volume 62, Issue 1, Pages 102-106 (January 2010)


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Desmoplastic trichoepithelioma

Adam J. Mamelak, MDab, Leonard H. Goldberg, MD, FRCPabCorresponding Author Informationemail address, Tracy M. Katz, MDb, Jeffery J. Graves, MDa, Ofer Arnon, MDc, Arash Kimyai-Asadi, MDb

Background

Desmoplastic trichoepithelioma (DTE) is an uncommon adnexal tumor usually found on the face of young women.

Objective

We sought to describe the clinical and histologic characteristics of DTE and discuss management strategies for these tumors.

Methods

We conducted a retrospective case series and review of the literature.

Results

A series of 17 cases of DTE is reported. Of our patients, 82% were female and half of all these cases occurred on the cheek. Unlike previous reports, the patients in our study were slightly older, with 53% older than 51 years and 71% between the ages of 31 and 60 years at the time of surgery (mean age 49 years, median age 52 years, range 14-81 years). Approximately 38% of the tumors had been present for 1 to 2 years before presentation. The average size of the tumors at the time of surgery was 0.8 × 0.6 cm. All cases were treated with Mohs micrographic surgery. To date, none of the tumors have recurred.

Limitations

This is a small case series. The referral patterns of our predominantly Mohs micrographic surgery clinic might further bias this study.

Conclusion

DTE is a benign tumor that has a predilection for the face. With its rapid growth, aggressive histologic features that may be confused with basal cell carcinoma, and tendency to arise in cosmetically and functionally sensitive areas, these tumors should be removed in a manner that assures clear surgical margins, such as Mohs micrographic surgery.

a Department of Dermatology, the Methodist Hospital, Houston, Texas

b DermSurgery Associates, Houston, Texas

c Department of Plastic and Reconstructive Surgery, Soroka University Medical Center, Beer-Sheva, Israel

Corresponding Author InformationCorrespondence to: Leonard H. Goldberg, MD, FRCP, 7515 Main, Suite 240, Houston, TX 77030.

 Funding sources: None.

 Conflicts of interest: None declared.

 Reprints not available from the authors.

PII: S0190-9622(09)00820-2

doi:10.1016/j.jaad.2009.06.066


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