Journal of the American Academy of Dermatology
Volume 62, Issue 1 , Pages 102-106 , January 2010

Desmoplastic trichoepithelioma

  • Adam J. Mamelak, MD

      Affiliations

    • Department of Dermatology, the Methodist Hospital, Houston, Texas
    • DermSurgery Associates, Houston, Texas
    • ,
  • Leonard H. Goldberg, MD, FRCP

      Affiliations

    • Department of Dermatology, the Methodist Hospital, Houston, Texas
    • DermSurgery Associates, Houston, Texas
    • Corresponding Author InformationCorrespondence to: Leonard H. Goldberg, MD, FRCP, 7515 Main, Suite 240, Houston, TX 77030.
    • ,
  • Tracy M. Katz, MD

      Affiliations

    • DermSurgery Associates, Houston, Texas
    • ,
  • Jeffery J. Graves, MD

      Affiliations

    • Department of Dermatology, the Methodist Hospital, Houston, Texas
    • ,
  • Ofer Arnon, MD

      Affiliations

    • Department of Plastic and Reconstructive Surgery, Soroka University Medical Center, Beer-Sheva, Israel
    • ,
  • Arash Kimyai-Asadi, MD

      Affiliations

    • DermSurgery Associates, Houston, Texas

References 

  1. Zeligman I. Solitary trichoepithelioma. Arch Dermatol. 1960;82:89–94
  2. MacDonald DM, Jones EW, Marks R. Sclerosing epithelial hamartoma. Clin Exp Dermatol. 1977;2:153–160
  3. Brownstein M, Shapiro L. Desmoplastic trichoepithelioma. Cancer. 1977;40:2979–2986
  4. Takei Y, Fukushiro S, Ackerman AB. Criteria for histologic differentiation of desmoplastic trichoepithelioma (sclerosing epithelial hamartoma) from morphea-like basal-cell carcinoma. Am J Dermatopathol. 1985;7:207–221
  5. Harada H, Hashimoto K, Ko MS. The gene for multiple familial trichoepithelioma maps to chromosome 9p21. J Invest Dermatol. 1996;107:41–43
  6. McCalmont TH. Adnexal neoplasms. In:  Bolognia JL,  Jorizzo JL,  Rapini RP editor. Dermatology. New York (NY): Mosby; 2003;p. 1733–1755
  7. Behroozan DS, Goldberg LH, Glaich AS, Kaplan B, Kaye VN. Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms. Dermatol Surg. 2006;32:958–965
  8. Izikson L, Bhan A, Zembowicz A. Androgen receptor expression helps to differentiate basal cell carcinoma from benign trichoblastic tumors. Am J Dermatopathol. 2005;27:91–95
  9. Kirchmann TT, Prieto VG, Smoller BR. CD34 staining pattern distinguishes basal cell carcinoma from trichoepithelioma. Arch Dermatol. 1994;130:589–592
  10. Hartschuh W, Schulz T. Merkel cells are integral constituents of desmoplastic trichoepithelioma: an immunohistochemical and electron microscopic study. J Cutan Pathol. 1995;22:413–421
  11. Swanson PE, Fitzpatrick MM, Ritter JH, Glusac EJ, Wick MR. Immunohistologic differential diagnosis of basal cell carcinoma, squamous cell carcinoma, and trichoepithelioma in small cutaneous biopsy specimens. J Cutan Pathol. 1998;25:153–159
  12. Kechijian P, Connors RC, Ackerman AB. Trichoepithelioma vs basal-cell carcinoma: criteria for histologic differentiation. J Dermatol Surg. 1975;1:22–23

 Funding sources: None.

 Conflicts of interest: None declared.

 Reprints not available from the authors.

PII: S0190-9622(09)00820-2

doi: 10.1016/j.jaad.2009.06.066

Journal of the American Academy of Dermatology
Volume 62, Issue 1 , Pages 102-106 , January 2010

Article Tools

* Image Usage & Resolution