Journal of the American Academy of Dermatology
Volume 63, Issue 5 , Pages 782-788 , November 2010

Underestimated clinical features of postadolescent acne

  • Bruno Capitanio, MD

      Affiliations

    • Pediatric Dermatology Department, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy
    • ,
  • Jo Linda Sinagra, MD

      Affiliations

    • Pediatric Dermatology Department, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy
    • Corresponding Author InformationReprint requests: Jo Linda Sinagra, MD, Pediatric Dermatology Department, San Gallicano Istituto di Ricerca e Cura a Carattere Scientifico, Via Elio Chianesi 53, 00144 Roma, Italy.
    • ,
  • Valentina Bordignon, PhD

      Affiliations

    • Department of Clinical Pathology and Microbiology, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy
    • ,
  • Paola Cordiali Fei, PhD

      Affiliations

    • Department of Clinical Pathology and Microbiology, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy
    • ,
  • Mauro Picardo, MD

      Affiliations

    • Cutaneous Physiopathology Department, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy
    • ,
  • Christos C. Zouboulis, MD

      Affiliations

    • Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Dessau, Germany

,Accepted 13 November 2009.

References 

  1. Ghodsi SZ, Orawa H, Zouboulis CC. Prevalence, severity and severity risk factors of acne in high school pupils: a community-based study. J Invest Dermatol. 2009;129:2136–2141
  2. Williams C, Layton AM. Persistent acne in women: implications for the patient and for therapy. Am J Clin Dermatol. 2006;7:281–290
  3. Orfanos CE, Adler YD, Zouboulis CC. The SAHA syndrome. Horm Res. 2000;54:251–258
  4. Capitanio B, Sinagra JL, Ottaviani M, Bordignon V, Amantea A, Picardo M. ‘Smoker's acne’: a new clinical entity?. Br J Dermatol. 2007;157:1070–1071
  5. Goulden V, Clark SM, Cunliffe WJ. Post adolescence acne: a review of clinical features. Br J Dermatol. 1997;136:66–70
  6. Kligman AM. Post adolescent acne in women. Cutis. 1991;48:75–77
  7. Knaggs HE, Wood EJ, Rizer RL, Mills OH. Post-adolescent acne. Int J Cosmet Sci. 2004;26:129–138
  8. Cerimele D, Celleno L, Serri F. Physiological changes in ageing skin. Br J Dermatol. 1990;122(Suppl):13–20
  9. Makrantonaki E, Adjaye J, Herwig R, Brink TC, Groth D, Hultschig C, et al. Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell. 2006;5:331–344
  10. Hayashi N, Akamatsu H, Kawashima M. Acne Study Group. Establishment of grading criteria for acne severity. J Dermatol. 2008;35:255–260
  11. Rivera AE. Acne scarring: a review and current treatment modalities. J Am Acad Dermatol. 2008;59:659–676
  12. Papakonstantinou E, Aletras AJ, Glass E, Tsogas P, Dionyssopoulos A, Adjaye J, et al. Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. J Invest Dermatol. 2005;125:673–684
  13. Cunliffe WJ. Androgen abnormalities in acne subjects. In: Acne. Martin Dunitz; Pub. London; 1989;p. 156-60
  14. Thiboutot D. Acne: hormonal concepts and therapy. Clin Dermatol. 2004;22:419–428
  15. Schäfer T, Nienhaus A, Vieluf D, Berger J, Ring J. Epidemiology of acne in the general population: the risk of smoking. Br J Dermatol. 2001;145:100–104
  16. Chuh AA, Zawar V, Wong WC, Lee A. The association of smoking and acne in men in Hong Kong and in India: a retrospective case-control study in primary care settings. Clin Exp Dermatol. 2004;29:597–599
  17. Mills CM, Peters TJ, Finlay AY. Does smoking influence acne?. Clin Exp Dermatol. 1993;18:100–101
  18. Klaz I, Kochba I, Shohat T, Zarka S, Brenner S. Severe acne vulgaris and tobacco smoking in young men. J Invest Dermatol. 2006;126:1749–1752
  19. Rombouts S, Nijsten T, Lambert J. Cigarette smoking and acne in adolescents: results from a cross-sectional study. J Eur Acad Dermatol Venereol. 2007;21:326–333
  20. Misery L. Nicotine effects on skin: are they positive or negative?. Exp Dermatol. 2004;13:665–670
  21. Kalayciyan A, Orawa H, Fimmel S, Perschel FH, González J-B, Fitzner RG, et al. Nicotine and biochanin A, but not cigarette smoke, induce anti-inflammatory effects on keratinocytes and endothelial cells in patients with Behçet's disease. J Invest Dermatol. 2007;127:81–89
  22. Kurzen H, Wessler I, Kirkpatrick CJ, Kawashima K, Grando SA. The non-neuronal cholinergic system of human skin. Horm Metab Res. 2007;39:125–135
  23. Zouboulis CC, Baron JM, Böhm M, Kippenberger S, Kurzen H, Reichrath J, et al. Frontiers in sebaceous gland biology and pathology. Exp Dermatol. 2008;17:542–551
  24. Zouboulis CC, Seltmann H, Hiroi N, Chen W, Young M, Oeff M, et al. Corticotropin releasing hormone: an autocrine hormone that promotes lipogenesis in human sebocytes. Proc Natl Acad Sci U S A. 2002;99:7148–7153
  25. Ganceviciene R, Graziene V, Fimmel S, Zouboulis CC. Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgaris. Br J Dermatol. 2009;160:345–352
  26. Wu TQ, Mei SQ, Zhang JX, Gong LF, Wu FJ, Wu WH, et al. Prevalence and risk factors of facial acne vulgaris among Chinese adolescents. Int J Adolesc Med Health. 2007;19:407–412
  27. Spencer EH, Ferdowsian HR, Barnard ND. Diet and acne: a review of the evidence. Int J Dermatol. 2009;48:339–347
  28. Kaymak Y, Adisen E, Ilter N, Bideci A, Gurler D, Celik B. Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients with acne. J Am Acad Dermatol. 2007;57:819–823

 Funding sources: None.

 Conflicts of interest: None declared.

PII: S0190-9622(09)01488-1

doi: 10.1016/j.jaad.2009.11.021

Journal of the American Academy of Dermatology
Volume 63, Issue 5 , Pages 782-788 , November 2010

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