Journal of the American Academy of Dermatology
Volume 40, Issue 6 , Pages 930-937 , June 1999

Finasteride in the treatment of men with frontal male pattern hair loss

These data were originally presented at Dermatology 19th World Congress, Australia, June 1997.

,Accepted 8 January 1999.

References 

  1. Olsen EA. Androgenetic alopecia. In:  Olsen EA editors. Disorders of hair growth: diagnosis and treatment. New York: McGraw-Hill; 1994;p. 257–283
  2. Hamilton JB. Male hormone stimulation is prerequisite and an incitant in common baldness. Am J Anat. 1942;71:451–480
  3. Hamilton JB. Patterned loss of hair in man: types and incidence. Ann N Y Acad Sci. 1951;53:708–728
  4. Imperato-McGinley J, Guerrero L, Gautier T, Peterson RE. Steroid 5α-reductase deficiency in man: an inherited form of male pseudohermaphroditism. Science. 1974;186:1213–1215
  5. Dallob AL, Sadick NS, Unger W, Lipert S, Geissler LA, Gregoire SL, et al.  The effect of finasteride, a 5α-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. J Clin Endocrinol Metab. 1994;79:703–706
  6. Waldstreicher J, Fiedler V, Hordinsky M, Swinehart JM, Thiboutot D, Unger W, et al.  Effects of finasteride on dihydrotestosterone content of scalp skin in men with male pattern baldness. [abstract] J Invest Dermatol. 1994;102:615
  7. Kaufman KD, Olsen EA, Whiting D, Savin R, DeVillez R, Bergfeld W, et al.  Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol. 1998;39:578–589
  8. Norwood OT. Male pattern baldness: classification and incidence. South Med J. 1975;68:1359–1365
  9. Takashima I, Iju M, Sudo M. Alopecia androgenetica—its incidence in Japanese and associated conditions. In:  Orfanos CE,  Montagna W,  Stüttgen G editor. Hair research: status and future aspects. New York: Springer-Verlag; 1981;p. 287–293
  10. Canfield D. Photographic documentation of hair growth in androgenetic alopecia. Dermatol Clin. 1996;14:713–721
  11. Barber B, Kaufman KD, Kozloff R, Girman CJ, Guess HA. A hair growth questionnaire for use in the evaluation of therapeutic effects in men. J Dermatol Treat. 1998;9:181–186
  12. Kaufman K, Binkowitz B, Savin R, Canfield D. Reproducibility of global photographic assessments of patients with male pattern baldness in a clinical trial with finasteride. [abstract] J Invest Dermatol. 1995;104:659

☆ The reported clinical study was entirely supported by Merck Research Laboratories, Merck & Co, Inc. Merck & Co, Inc is the company that manufactures and markets finasteride.

☆☆ A full conflict of interest statement from each of the authors has been submitted to the Editor. One or more of the authors have received payment for conducting the study, acted as consultants to the sponsoring company, received honoraria for lecturing, or owned stock in the sponsoring company.

★ Reprint requests: Joanne Waldstreicher, MD, Clinical Research RY33-508, Merck Research Laboratories, 126 E Lincoln Ave, Rahway, NJ 07065.

★★ 0190-9622/99/$8.00 + 0  16/1/96937

PII: S0190-9622(99)70081-2

Journal of the American Academy of Dermatology
Volume 40, Issue 6 , Pages 930-937 , June 1999

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