| Continuing Medical Education |
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Solar cheilosis: An ominous precursor: Part I. Diagnostic insights
Squamous cell carcinoma (SCC) of the lower lip is a deadly nonmelanoma skin cancer. Its precursor, a distinctive cutaneous neoplasia analogous to cervical dysplasia, is known by the confusing term act...
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Yuri T. Jadotte,
Robert A. Schwartz
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173-184
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CME examination
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185
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Answers to CME examination
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186
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Change of Address
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186
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Solar cheilosis: An ominous precursor: Part II. Therapeutic perspectives
The differential diagnosis of SC includes malignant, premalignant, metastatic, inflammatory, and eczematoid disorders, along with photodermatoses and a few rare but important disorders of the lower li...
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Yuri T. Jadotte,
Robert A. Schwartz
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187-198
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CME examination
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199
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Answers to CME examination
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200
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American Board of Dermatology Examination Dates
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200
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| Original Articles |
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Systematic skin cancer screening in Northern Germany
10 November 2011
Background: The incidence of skin cancer is increasing worldwide. For decades, opportunistic melanoma screening has been carried out to respond to this burden. However, despite potential positive effe...
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Eckhard W. Breitbart,
Annika Waldmann,
Sandra Nolte,
Marcus Capellaro,
Ruediger Greinert,
Beate Volkmer,
Alexander Katalinic
et al.
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201-211
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Total body skin examination for skin cancer screening in patients with focused symptoms
15 July 2011
Background: The value of total body skin examination (TBSE) for skin cancer screening is controversial. Objective: We sought to determine whether TBSE could be helpful in patients with focused skin sy...
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Giuseppe Argenziano,
Iris Zalaudek,
Rainer Hofmann-Wellenhof,
Renato Marchiori Bakos,
Wilma Bergman,
Andreas Blum,
Paolo Broganelli,
Horacio Cabo,
Filomena Caltagirone,
Caterina Catricalà,
Maurizio Coppini,
Lucas Dewes,
Maria Grazia Francia,
Alessandro Garrone,
Bengu Gerceker Turk,
Giovanni Ghigliotti,
Jason Giacomel,
Jean-Yves Gourhant,
Gerald Hlavin,
Nicole Kukutsch,
Dario Lipari,
Gennaro Melchionda,
Fezal Ozdemir,
Giovanni Pellacani,
Riccardo Pellicano,
Susana Puig,
Massimiliano Scalvenzi,
Ana Maria Sortino-Rachou,
Anna Rosa Virgili,
Harald Kittler
et al.
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212-219
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Prevalence of self-report photosensitivity in cutaneous lupus erythematosus
11 July 2011
Background: Little is known about the prevalence of self-reported photosensitivity (PS) and its effects on quality of life in a US cutaneous lupus population. Objective: We sought to determine the pre...
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Kristen Foering,
Renato Goreshi,
Rachel Klein,
Joyce Okawa,
Mathew Rose,
Andrew Cucchiara,
Victoria P. Werth
et al.
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220-228
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Positive patch test reactions in older individuals: Retrospective analysis from the North American Contact Dermatitis Group, 1994-2008
20 May 2011
Background: Relatively little is known about the epidemiology of allergic contact dermatitis in older individuals. Objectives: We sought to determine the frequency of positive and clinically relevant ...
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Erin M. Warshaw,
Srihari I. Raju,
Joseph F. Fowler,
Howard I. Maibach,
Donald V. Belsito,
Kathryn A. Zug,
Robert L. Rietschel,
James S. Taylor,
C. G. Toby Mathias,
Anthony F. Fransway,
Vincent A. DeLeo,
James G. Marks,
Frances J. Storrs,
Melanie D. Pratt,
Denis Sasseville
et al.
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229-240
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Long-term efficacy and safety of adalimumab in patients with moderate to severe psoriasis treated continuously over 3 years: Results from an open-label extension study for patients from REVEAL
15 July 2011
Background: REVEAL was a 52-week phase III trial of adalimumab therapy for moderate to severe chronic plaque psoriasis. Patients from REVEAL could enter an open-label extension trial to receive adalim...
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Kenneth Gordon,
Kim Papp,
Yves Poulin,
Yihua Gu,
Stephen Rozzo,
Eric H. Sasso
et al.
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241-251
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Psoriasis and cardiovascular risk factors: A case-control study on inpatients comparing psoriasis to dermatitis
11 July 2011
Background: Previous reports demonstrated an association between psoriasis and cardiovascular disease (CVD) risk factors. However, most of these studies were based on computerized databases of outpati...
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Jonathan Shapiro,
Arnon David Cohen,
Dahlia Weitzman,
Roy Tal,
Michael David
et al.
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252-258
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Familial multiple discoid fibromas: A look-alike of Birt-Hogg-Dubé syndrome not linked to the FLCN locus
27 July 2011
Background: Previously, we proposed that familial multiple trichodiscomas (OMIM 190340) is distinct from Birt-Hogg-Dubé syndrome (BHD) (OMIM #135150). BHD is characterized by multiple fibrofolliculoma...
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Theo M. Starink,
Arjan C. Houweling,
Martijn B.A. van Doorn,
Edward M. Leter,
Elisabeth H. Jaspars,
R. Jeroen A. van Moorselaar,
Piet E. Postmus,
Paul C. Johannesma,
Jan Hein van Waesberghe,
Martijn H. Ploeger,
Marieke T. Kramer,
Johan J.P. Gille,
Quinten Waisfisz,
Fred H. Menko
et al.
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259.e1-259.e9
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The efficacy of trimethoprim in wound healing of patients with epidermolysis bullosa: A feasibility trial
08 December 2011
Background: There are no systemic therapies known to facilitate wound healing in patients with recessive dystrophic epidermolysis bullosa (RDEB). Objectives: We sought to assess the feasibility of a t...
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Irene Lara-Corrales,
Patricia C. Parkin,
Derek Stephens,
Jill Hamilton,
Gideon Koren,
Miriam Weinstein,
Ronald G. Sibbald,
Elena Pope
et al.
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264-270
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| Dermatologic Surgery |
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Optimal tattoo removal in a single laser session based on the method of repeated exposures
31 October 2011
Background: Unwanted tattoos are treated with Q-switched lasers. Despite a series of treatments, efficacy is limited. Objective: We compared a single Q-switched laser treatment pass with 4 treatment p...
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Theodora Kossida,
Dimitrios Rigopoulos,
Andreas Katsambas,
R. Rox Anderson
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271-277
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| Dermatopathology |
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Clinicopathological features and prognostic significance of CXCL12 in blastic plasmacytoid dendritic cell neoplasm
12 August 2011
Background: Blastic plasmacytoid dendritic cell neoplasm (BPDC) is a rare hematologic neoplasm, which almost always involves the skin and shows poor prognosis. Objective: The aim of our study was to e...
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Keiko Hashikawa,
Daisuke Niino,
Shinichiro Yasumoto,
Takekuni Nakama,
Junichi Kiyasu,
Kensaku Sato,
Yoshizo Kimura,
Masanori Takeuchi,
Yasuo Sugita,
Takashi Hashimoto,
Koichi Ohshima
et al.
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278-291
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| Reviews |
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Generalized verrucosis: A review of the associated diseases, evaluation, and treatments
16 May 2011
Generalized verrucosis has been described in the past as synonymous with epidermodysplasia verruciformis. It has been shown, however, that epidermodysplasia verruciformis and other genetic or immunode...
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Jennifer C. Sri,
Meghan I. Dubina,
Grace F. Kao,
Peter L. Rady,
Stephen K. Tyring,
Anthony A. Gaspari
et al.
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292-311
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Pompholyx and eczematous reactions associated with intravenous immunoglobulin therapy
23 May 2011
Introduction: Intravenous immunoglobulin (IVIG) is used to treat many inflammatory and autoimmune disorders and although generally well tolerated, cutaneous side effects occur. Objective: We reviewed ...
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Meg R. Gerstenblith,
Ashley K. Antony,
Jacqueline M. Junkins-Hopkins,
Rachel Abuav
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312-316
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| Commentary |
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Biopharmaceuticals and biosimilars in psoriasis: What the dermatologist needs to know
The entry of biosimilar forms of biopharmaceutical therapies for the treatment of psoriasis and other immune-mediated disorders has provoked considerable interest. Although dermatologists are accustom...
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Bruce E. Strober,
Katherine Armour,
Ricardo Romiti,
Catherine Smith,
Paul W. Tebbey,
Alan Menter,
Craig Leonardi
et al.
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317-322
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| Letters |
| Notes & Comments |
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Limitations of the “spaghetti technique”
To the Editor: We read with great interest the recent article by Gaudy-Marqueste et al entitled “The ‘‘spaghetti technique’’: An alternative to Mohs surgery or staged surgery for problematic lentigino...
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Navid Bouzari,
Emily J. Fisher,
Mollie A. MacCormack,
Suzanne Olbricht
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323-324
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Segmentally grouped melanocytic nevi and melanoma risk
To the Editor: In the June 2011 issue of the JAAD, Ly et al reported a 4-case series on malignant melanoma (MM) arising on speckled lentiginous nevus (SLN). It is my opinion that none of those cases c...
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Daniele Torchia
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324-325
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Reply
To the Editor: We would disagree with the primary argument put forward by Torchia in response to our article “Melanoma(s) arising in large segmental speckled lentiginous nevi (SLN): A case series,” wh...
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Lena Ly,
Ingrid Winship,
John William Kelly
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325-326
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Long-term prognosis of vitiligo patients on narrowband UVB phototherapy
To the Editor: We read with interest the CME article on vitiligo that mentioned the paucity of long-term follow-up data of narrowband ultraviolet B (NB-UVB) therapy in vitiligo. Although there are no ...
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Kelly K. Park,
Jenny E. Murase,
John Koo
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326-327
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| Research Letters |
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Randomized study of topical tacrolimus ointment as possible treatment for resistant idiopathic pruritus ani
To the Editor: Pruritus ani (PA) is a common and embarrassing proctologic condition, which can be difficult to treat if there are no obvious predisposing factors. There is little scientific evidence c...
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Erwin Suys
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327-328
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Infliximab as a steroid-sparing agent in refractory cutaneous sarcoidosis: Single-center retrospective study of 9 patients
To the Editor: Therapeutic options for cutaneous sarcoidosis are limited. Several reports of successful treatment of cutaneous sarcoidosis with anti-tumor necrosis factor have been published. We aimed...
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Thomas Sené,
Caroline Juillard,
Michel Rybojad,
Florence Cordoliani,
Céleste Lebbé,
Patrice Morel,
Abdellatif Tazi,
Fabien Guibal
et al.
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328-332
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| Case Letters |
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Grover disease may result from the impairment of keratinocytic cholinergic receptors
To the Editor: Grover disease is an eruption of intraepidermal acantholysis presenting as crusted reddened papules; it is usually found on the trunk of middle aged patients, with a male to female rati...
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David Paslin
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332-333
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Phaeohyphomycosis caused by Phaeoacremonium species in a patient taking infliximab
To the Editor: We report a 74-year-old man with a history of severe rheumatoid arthritis treated with infliximab who presented with a slowly enlarging nodule on his posterior left leg. The lesion bega...
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Jason D. Mazzurco,
James Ramirez,
David P. Fivenson
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333-335
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Use of a hydrocolloid dressing to aid in the closure of surgical wounds in patients with fragile skin
To the Editor: When repairing surgical defects in patients with thin, fragile skin, it can sometimes be difficult to suture wounds without tearing through cutaneous layers, particularly for distal ext...
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Jason D. Mazzurco,
Kent Jerome Krach
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335-336
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| JAAD Grand Rounds |
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JAAD Grand Rounds quiz∗ A 46-year-old man with agminated papules on the buttock
Instructions: In answering each question, refer to the specific directions provided. Because it is often necessary to provide information occurring later in a series that gives away answers to earlier...
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Marsha D. Mitchum,
Erin G. Adams,
Katherine Z. Holcomb
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337-339
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A 40-year-old man with hyperkeratotic palms and soles
A 40-year-old Hispanic man presented with thickened, fissured, and peeling palms and soles that had been present since childhood (). He was seen for a refill of his medication (acitretin 25 mg/day), w...
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Joy D. Wisniewski,
Rashid M. Rashid,
Carolyn A. Bangert
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339-341
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Red, purple, and brown skin lesions in a 2-month-old boy
A 2-month-old boy presented with a homogenous and reticulated erythematous patch involving the right side of his face, mainly in the distribution of cranial nerve V1/V2 (). This erythematous to purple...
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Jeffrey R. Smith,
Mary M. Moore,
Cloyce L. Stetson
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341-342
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| Images in Dermatology |
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An infant with persistent bullous urticaria
A 6-month-old male presents with persistent urticaria that has been present since 1 month of age and that began after starting a course of oral ranitidine. The physical examination reveals striking de...
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Jeffrey Mailhot,
Silvina Pugliese,
Rujing Han,
Karen Wiss
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e29-e30
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Erosive plaques on the dorsal surfaces of the hands
An otherwise healthy 58-year-old woman presents with a 10-day history of ulcers on the dorsal surfaces of both hands. The initial lesion, an expanding pustule, became bullous and erosive. She subseque...
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Jenny A. Mandell,
Brook E. Tlougan,
Ali Jabbari,
Ruth F. Walters,
Roopal V. Kundu
et al.
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e31-e32
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| JAAD Online |
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Assessment of the long-term safety and effectiveness of etanercept for the treatment of psoriasis in an adult population
20 September 2010
Background: Etanercept is well tolerated and effective in moderate to severe plaque psoriasis. However, effectiveness and safety data beyond 2.5 years have not been reported. Objective: We sought to a...
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Kim A. Papp,
Yves Poulin,
Robert Bissonnette,
Marc Bourcier,
Darryl Toth,
Leslie Rosoph,
Melanie Poulin-Costello,
Mike Setterfield,
Jerry Syrotuik
et al.
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e33-e45
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In vivo reflectance confocal microscopy of extramammary Paget disease: Diagnostic evaluation and surgical management
27 May 2011
Background: Extramammary Paget disease (EMPD) is a diagnostic challenge. In vivo reflectance confocal microscopy (RCM) has been reported to be useful for in vivo skin tumor evaluation. It may also ass...
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Zhan-Yan Pan,
Jun Liang,
Qiao-An Zhang,
Jing-Ran Lin,
Zhi-Zhong Zheng
et al.
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e47-e53
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Cutaneous small-vessel vasculitis associated with solid organ malignancies: The Mayo Clinic experience, 1996 to 2009
19 November 2010
Background: Although rare, cutaneous small-vessel vasculitis (CSVV) secondary to solid organ malignancy has been documented. Objective: We sought to better understand the frequency, clinical course, t...
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Joshua O. Podjasek,
David A. Wetter,
Mark R. Pittelkow,
David A. Wada
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e55-e65
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The effects of adalimumab treatment and psoriasis severity on self-reported work productivity and activity impairment for patients with moderate to severe psoriasis
26 May 2011
Background: Psoriasis significantly impairs work productivity and daily activities. Objectives: We sought to examine the effects of adalimumab on psoriasis-related work productivity and activity impai...
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Alexa Boer Kimball,
Andrew P. Yu,
James Signorovitch,
Jipan Xie,
Magda Tsaneva,
Shiraz R. Gupta,
Yanjun Bao,
Parvez M. Mulani
et al.
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e67-e76
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Iotaderma #217
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Robert I. Rudolph
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e77
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January iotaderma (#216)
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Robert I. Rudolph
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e77-e78
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| Frontmatter |
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Editorial Board
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A2
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Table of Contents
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A5-A6
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Information for Readers
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A29-A30
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Dermatology Calendar
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A49
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